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DOT1L inhibitors block abnormal self-renewal induced by cohesin loss.
Heimbruch, Katelyn E; Fisher, Joseph B; Stelloh, Cary T; Phillips, Emily; Reimer, Michael H; Wargolet, Adam J; Meyer, Alison E; Pulakanti, Kirthi; Viny, Aaron D; Loppnow, Jessica J; Levine, Ross L; Pulikkan, John Anto; Zhu, Nan; Rao, Sridhar.
Afiliación
  • Heimbruch KE; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Fisher JB; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Stelloh CT; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Phillips E; Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI, USA.
  • Reimer MH; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Wargolet AJ; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Meyer AE; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Pulakanti K; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Viny AD; Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI, USA.
  • Loppnow JJ; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Levine RL; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Pulikkan JA; Department of Medicine, Division of Hematology and Oncology, and Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY, USA.
  • Zhu N; Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI, USA.
  • Rao S; Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Department of Pathology, Molecular Cytology Core Facility, and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sci Rep ; 11(1): 7288, 2021 03 31.
Article en En | MEDLINE | ID: mdl-33790356
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Proteínas Cromosómicas no Histona / Leucemia Mieloide Aguda / N-Metiltransferasa de Histona-Lisina / Proteínas de Ciclo Celular / Autorrenovación de las Células Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Proteínas Cromosómicas no Histona / Leucemia Mieloide Aguda / N-Metiltransferasa de Histona-Lisina / Proteínas de Ciclo Celular / Autorrenovación de las Células Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos