Knockdown of lncRNA PVT1 attenuated macrophage M1 polarization and relieved sepsis induced myocardial injury via miR-29a/HMGB1 axis.

Luo, Yuan-Yuan; Yang, Zhong-Qi; Lin, Xin-Feng; Zhao, Feng-Li; Tu, Hai-Tao; Wang, Ling-Jun; Wen, Min-Yong; Xian, Shao-Xiang

Luo, Yuan-Yuan; Yang, Zhong-Qi; Lin, Xin-Feng; Zhao, Feng-Li; Tu, Hai-Tao; Wang, Ling-Jun; Wen, Min-Yong; Xian, Shao-Xiang.

Afiliación

Luo YY; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China.
Yang ZQ; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China.
Lin XF; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China.
Zhao FL; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China.
Tu HT; Department of Nephrology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China.
Wang LJ; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China. Electronic address: linjunn789@163.com.
Wen MY; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China. Electronic address: mmyon456@163.com.
Xian SX; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, PR China. Electronic address: shaaxx123@163.com.

Cytokine ; 143: 155509, 2021 07.

Article en En | MEDLINE | ID: mdl-33840587

Asunto(s)

Polaridad Celular; Técnicas de Silenciamiento del Gen; Proteína HMGB1/metabolismo; Macrófagos/metabolismo; MicroARNs/metabolismo; Miocardio/patología; ARN Largo no Codificante/metabolismo; Sepsis/genética; Animales; Secuencia de Bases; Polaridad Celular/genética; Pruebas de Función Cardíaca; Inflamación/genética; Inflamación/patología; Lipopolisacáridos; Masculino; Ratones Endogámicos C57BL; MicroARNs/genética; ARN Largo no Codificante/genética; Transducción de Señal; Regulación hacia Arriba/genética

Palabras clave

HMGB1; Macrophage polarization; Myocardial injury; Sepsis; lncRNA PVT1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polaridad Celular / Sepsis / Proteína HMGB1 / MicroARNs / Técnicas de Silenciamiento del Gen / ARN Largo no Codificante / Macrófagos / Miocardio Límite: Animals Idioma: En Revista: Cytokine Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article

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