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Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.
Inoue, Daichi; Polaski, Jacob T; Taylor, Justin; Castel, Pau; Chen, Sisi; Kobayashi, Susumu; Hogg, Simon J; Hayashi, Yasutaka; Pineda, Jose Mario Bello; El Marabti, Ettaib; Erickson, Caroline; Knorr, Katherine; Fukumoto, Miki; Yamazaki, Hiromi; Tanaka, Atsushi; Fukui, Chie; Lu, Sydney X; Durham, Benjamin H; Liu, Bo; Wang, Eric; Mehta, Sanjoy; Zakheim, Daniel; Garippa, Ralph; Penson, Alex; Chew, Guo-Liang; McCormick, Frank; Bradley, Robert K; Abdel-Wahab, Omar.
Afiliación
  • Inoue D; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Polaski JT; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Taylor J; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Castel P; Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, Miami, FL, USA.
  • Chen S; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
  • Kobayashi S; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Hogg SJ; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Hayashi Y; Division of Cellular Therapy, The Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Pineda JMB; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • El Marabti E; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Erickson C; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Knorr K; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
  • Fukumoto M; Medical Scientist Training Program, University of Washington, Seattle, WA, USA.
  • Yamazaki H; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Tanaka A; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Fukui C; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Lu SX; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Durham BH; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Liu B; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Wang E; Department of Immunology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.
  • Mehta S; Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan.
  • Zakheim D; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Garippa R; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Penson A; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • Chew GL; Human Oncology and Pathogenesis Program, Memorial Sloan KetterAbsolute numbers of live mature hematopoietic cellsing Cancer Center, New York, NY, USA.
  • McCormick F; Gene Editing & Screening Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bradley RK; Gene Editing & Screening Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Abdel-Wahab O; Gene Editing & Screening Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Genet ; 53(5): 707-718, 2021 05.
Article en En | MEDLINE | ID: mdl-33846634

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Intrones / Predisposición Genética a la Enfermedad / Enfermedades Hematológicas / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Japón

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Intrones / Predisposición Genética a la Enfermedad / Enfermedades Hematológicas / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Japón