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DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells.
Lim, Jung-Yeon; Duttke, Sascha H; Baker, Turner S; Lee, Jihye; Gambino, Kristyne J; Venturini, Nicholas J; Ho, Jessica Sook Yuin; Zheng, Simin; Fstkchyan, Yesai S; Pillai, Vinodh; Fajgenbaum, David C; Marazzi, Ivan; Benner, Christopher; Byun, Minji.
Afiliación
  • Lim JY; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Duttke SH; Department of Medicine, University of California, San Diego, La Jolla, CA.
  • Baker TS; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Lee J; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Gambino KJ; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Venturini NJ; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Ho JSY; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Zheng S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Fstkchyan YS; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Pillai V; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.
  • Fajgenbaum DC; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Marazzi I; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Benner C; Department of Medicine, University of California, San Diego, La Jolla, CA.
  • Byun M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
J Exp Med ; 218(7)2021 07 05.
Article en En | MEDLINE | ID: mdl-33970190
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Secuencias Reguladoras de Ácidos Nucleicos / Metilación de ADN / ADN (Citosina-5-)-Metiltransferasas / Haploinsuficiencia / Sistema Inmunológico Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Exp Med Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Secuencias Reguladoras de Ácidos Nucleicos / Metilación de ADN / ADN (Citosina-5-)-Metiltransferasas / Haploinsuficiencia / Sistema Inmunológico Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Exp Med Año: 2021 Tipo del documento: Article