A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.

Kulke, Martin; Nagel, Felix; Schulig, Lukas; Geist, Norman; Gabor, Marcel; Mayerle, Julia; M Lerch, Markus; Link, Andreas; Delcea, Mihaela

Kulke, Martin; Nagel, Felix; Schulig, Lukas; Geist, Norman; Gabor, Marcel; Mayerle, Julia; M Lerch, Markus; Link, Andreas; Delcea, Mihaela.

Afiliación

Kulke M; Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Nagel F; Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Schulig L; Institute of Pharmacy, University of Greifswald, Greifswald, Germany.
Geist N; Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Gabor M; Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Mayerle J; Department of Medicine II, Ludwig-Maximilian University of Munich, Munich, Germany.
M Lerch M; Department of Medicine a, University Medicine Greifswald, Greifswald, Germany.
Link A; Institute of Pharmacy, University of Greifswald, Greifswald, Germany.
Delcea M; Institute of Biochemistry, University of Greifswald, Greifswald, Germany.

J Inflamm Res ; 14: 2111-2119, 2021.

Article en En | MEDLINE | ID: mdl-34054303

Palabras clave

molecular dynamics simulations; replica exchange; transition path sampling; trypsin; umbrella sampling

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Inflamm Res Año: 2021 Tipo del documento: Article País de afiliación: Alemania

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