Ursodeoxycholic acid in the treatment of pregnancy cholestasis: a data-set available for Meta-analyses.
J Matern Fetal Neonatal Med
; 35(25): 7968-7971, 2022 Dec.
Article
en En
| MEDLINE
| ID: mdl-34134582
ABSTRACT
BACKGROUND:
The recent literature on intrahepatic cholestasis of pregnancy raises questions on the best management of such a disease. Improved evidence might be achieved by meta-analyses.AIM:
Providing data for allowing individual patients meta-analyses and aggregate data meta-analyses.METHODS:
Data were collected retrospectively at the Fabia Mater Hospital of Rome (Italy), between 2013 and 2018. Several variables were collected and analyzed according to low-level bile acid (less than 40 µmol/L) and high-level bile acid (at least 40 µmol/L). Eighty-three cases of pregnancy cholestasis, diagnosed according to itching symptoms and excluding bile diseases, were collected and analyzed, both descriptively and inferentially.CONCLUSION:
The analyzed data do not provide significant evidence supporting the use of ursodeoxycholic acid to prevent composite adverse fetal outcomes but they can be included in further meta-analyses.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Colestasis Intrahepática
Tipo de estudio:
Observational_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Asunto de la revista:
OBSTETRICIA
/
PERINATOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Italia