Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism.

Abbey, Deepti; Conlon, Donna; Rainville, Christopher; Elwyn, Susannah; Quiroz-Figueroa, Katherine; Billheimer, Jeffrey; Schultz, David C; Hand, Nicholas J; Cherry, Sara; Rader, Daniel J

Abbey, Deepti; Conlon, Donna; Rainville, Christopher; Elwyn, Susannah; Quiroz-Figueroa, Katherine; Billheimer, Jeffrey; Schultz, David C; Hand, Nicholas J; Cherry, Sara; Rader, Daniel J.

Afiliación

Abbey D; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Conlon D; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rainville C; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Elwyn S; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Quiroz-Figueroa K; High Throughput Screening Core, Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Billheimer J; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Schultz DC; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hand NJ; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cherry S; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rader DJ; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Clin Transl Sci ; 14(4): 1369-1379, 2021 07.

Article en En | MEDLINE | ID: mdl-34156146

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/metabolismo; Hepatocitos/metabolismo; Metabolismo de los Lípidos; Proteínas Nucleares/metabolismo; Triglicéridos/metabolismo; Proteínas Adaptadoras Transductoras de Señales/análisis; Proteínas Adaptadoras Transductoras de Señales/antagonistas & inhibidores; Proteínas Adaptadoras Transductoras de Señales/genética; Línea Celular Tumoral; Hígado Graso/tratamiento farmacológico; Hígado Graso/metabolismo; Hígado Graso/patología; Técnicas de Silenciamiento del Gen; Ensayos Analíticos de Alto Rendimiento; Humanos; Gotas Lipídicas/metabolismo; Proteínas Nucleares/análisis; Proteínas Nucleares/antagonistas & inhibidores; Proteínas Nucleares/genética; Triglicéridos/análisis

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triglicéridos / Proteínas Nucleares / Hepatocitos / Proteínas Adaptadoras Transductoras de Señales / Metabolismo de los Lípidos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Clin Transl Sci Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google