Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.

Medina, Christopher B; Chiu, Yu-Hsin; Stremska, Marta E; Lucas, Christopher D; Poon, Ivan; Tung, Kenneth S; Elliott, Michael R; Desai, Bimal; Lorenz, Ulrike M; Bayliss, Douglas A; Ravichandran, Kodi S

Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.

Medina, Christopher B; Chiu, Yu-Hsin; Stremska, Marta E; Lucas, Christopher D; Poon, Ivan; Tung, Kenneth S; Elliott, Michael R; Desai, Bimal; Lorenz, Ulrike M; Bayliss, Douglas A; Ravichandran, Kodi S.

Afiliación

Medina CB; Center for Cell Clearance, University of Virginia, Charlottesville, VA 22908, USA; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.
Chiu YH; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA; Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu, 30071, Taiwan.
Stremska ME; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.
Lucas CD; Center for Cell Clearance, University of Virginia, Charlottesville, VA 22908, USA.
Poon I; Department of Biochemistry and Genetics, La Trobe University, Melbourne, VIC 3083, Australia.
Tung KS; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA; Carter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA.
Elliott MR; Center for Cell Clearance, University of Virginia, Charlottesville, VA 22908, USA; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.
Desai B; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Lorenz UM; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA; Carter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA.
Bayliss DA; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Ravichandran KS; Center for Cell Clearance, University of Virginia, Charlottesville, VA 22908, USA; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA; Carter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA; VIB/UGent Inflamma

Immunity ; 54(8): 1715-1727.e7, 2021 08 10.

Article en En | MEDLINE | ID: mdl-34283971

Asunto(s)

Asma/inmunología; Comunicación Celular/inmunología; Conexinas/metabolismo; Proteínas del Tejido Nervioso/metabolismo; Proteínas Serina-Treonina Quinasas/metabolismo; Linfocitos T Reguladores/inmunología; Animales; Línea Celular; Proliferación Celular/fisiología; Conexinas/genética; Modelos Animales de Enfermedad; Células HEK293; Humanos; Células Jurkat; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Proteínas del Tejido Nervioso/genética; Sistema Respiratorio/inmunología

Palabras clave

Pannexin 1, extracellular ATP, lung, asthma, airway inflammation, T regulatory cell, T effector cell, Salt-inducible kinase, CD4 T cell, adenosine

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Asma / Comunicación Celular / Proteínas Serina-Treonina Quinasas / Linfocitos T Reguladores / Conexinas / Proteínas del Tejido Nervioso Límite: Animals / Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google