Dealing with transcription-blocking DNA damage: Repair mechanisms, RNA polymerase II processing and human disorders.

Jia, Nan; Guo, Chaowan; Nakazawa, Yuka; van den Heuvel, Diana; Luijsterburg, Martijn S; Ogi, Tomoo

Jia, Nan; Guo, Chaowan; Nakazawa, Yuka; van den Heuvel, Diana; Luijsterburg, Martijn S; Ogi, Tomoo.

Afiliación

Jia N; Department of Allergy and Clinical Immunology, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China; Department of
Guo C; Department of Genetics, Research Institute of Environmental Medicine (RIeM), Nagoya University, Nagoya, Japan; Department of Human Genetics and Molecular Biology, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Nakazawa Y; Department of Genetics, Research Institute of Environmental Medicine (RIeM), Nagoya University, Nagoya, Japan; Department of Human Genetics and Molecular Biology, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
van den Heuvel D; Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Luijsterburg MS; Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, The Netherlands. Electronic address: S.M.Luijsterburg@lumc.nl.
Ogi T; Department of Genetics, Research Institute of Environmental Medicine (RIeM), Nagoya University, Nagoya, Japan; Department of Human Genetics and Molecular Biology, Graduate School of Medicine, Nagoya University, Nagoya, Japan. Electronic address: togi@riem.nagoya-u.ac.jp.

DNA Repair (Amst) ; 106: 103192, 2021 10.

Article en En | MEDLINE | ID: mdl-34358806

Asunto(s)

Daño del ADN; Reparación del ADN; Inestabilidad Genómica; ARN Polimerasa II/metabolismo; Transcripción Genética; Envejecimiento; Animales; ADN/metabolismo; Eucariontes/enzimología; Eucariontes/genética; Eucariontes/metabolismo; Humanos

Palabras clave

Ageing-associated symptoms; Nucleotide excision repair; Transcription-blocking DNA lesions; Transcription-coupled repair; Ubiquitination of RNA polymerase II

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Daño del ADN / ARN Polimerasa II / Inestabilidad Genómica / Reparación del ADN Límite: Animals / Humans Idioma: En Revista: DNA Repair (Amst) Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2021 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google