<i>N<sup>6</sup></i> -methyladenosine-Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression.

Deng, Junge; Zhang, Jialiang; Ye, Ying; Liu, Kaijing; Zeng, Lingxing; Huang, Jingyi; Pan, Ling; Li, Mei; Bai, Ruihong; Zhuang, Lisha; Huang, Xudong; Wu, Guandi; Wei, Lusheng; Zheng, Yanfen; Su, Jiachun; Zhang, Shaoping; Chen, Rufu; Lin, Dongxin; Zheng, Jian

N⁶ -methyladenosine-Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression.

Deng, Junge; Zhang, Jialiang; Ye, Ying; Liu, Kaijing; Zeng, Lingxing; Huang, Jingyi; Pan, Ling; Li, Mei; Bai, Ruihong; Zhuang, Lisha; Huang, Xudong; Wu, Guandi; Wei, Lusheng; Zheng, Yanfen; Su, Jiachun; Zhang, Shaoping; Chen, Rufu; Lin, Dongxin; Zheng, Jian.

Afiliación

Deng J; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhang J; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Ye Y; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Liu K; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zeng L; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Huang J; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Pan L; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Li M; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.
Bai R; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhuang L; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Huang X; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wu G; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wei L; Department of Pancreaticobiliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Zheng Y; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Su J; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhang S; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chen R; Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital, Guangzhou, China.
Lin D; State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Guangzhou, Sun Yat-sen University Cancer Center, Guangzhou, China. zhengjian@sysucc.org.cn lindx@sysucc.org.cn.
Zheng J; Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Cancer Res ; 81(20): 5268-5283, 2021 10 15.

Article en En | MEDLINE | ID: mdl-34362795

Asunto(s)

Adenosina/análogos & derivados; Carcinoma Ductal Pancreático/patología; Proteínas de Ciclo Celular/metabolismo; Neoplasias Pancreáticas/patología; Biosíntesis de Proteínas; Factores de Empalme de ARN/metabolismo; ARN Largo no Codificante/genética; Vía de Señalización Wnt; Adenosina/química; Animales; Apoptosis; Biomarcadores de Tumor/genética; Biomarcadores de Tumor/metabolismo; Carcinoma Ductal Pancreático/genética; Carcinoma Ductal Pancreático/metabolismo; Proteínas de Ciclo Celular/genética; Proliferación Celular; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Neoplasias Pancreáticas/genética; Neoplasias Pancreáticas/metabolismo; Pronóstico; Factores de Empalme de ARN/genética; Tasa de Supervivencia; Activación Transcripcional; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Biosíntesis de Proteínas / Adenosina / Proteínas de Ciclo Celular / Carcinoma Ductal Pancreático / Vía de Señalización Wnt / ARN Largo no Codificante / Factores de Empalme de ARN Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2021 Tipo del documento: Article País de afiliación: China

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