The interaction of Epstein-Barr virus encoded transcription factor EBNA2 with multiple sclerosis risk loci is dependent on the risk genotype.

Keane, Jeremy Thomas; Afrasiabi, Ali; Schibeci, Stephen Donald; Swaminathan, Sanjay; Parnell, Grant Peter; Booth, David Richmond

Keane, Jeremy Thomas; Afrasiabi, Ali; Schibeci, Stephen Donald; Swaminathan, Sanjay; Parnell, Grant Peter; Booth, David Richmond.

Afiliación

Keane JT; Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.
Afrasiabi A; Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia; BioMedical Machine Learning Lab, The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW 2052, Australia.
Schibeci SD; Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.
Swaminathan S; Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia; Department of Medicine, Western Sydney University, Sydney, NSW 2560, Australia.
Parnell GP; Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia. Electronic address: grant.parnell@sydney.edu.au.
Booth DR; Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia. Electronic address: david.booth@sydney.edu.au.

EBioMedicine ; 71: 103572, 2021 Sep.

Article en En | MEDLINE | ID: mdl-34488019

Asunto(s)

Antígenos Nucleares del Virus de Epstein-Barr/metabolismo; Esclerosis Múltiple/genética; Factores de Transcripción/metabolismo; Alelos; Proteínas Reguladoras de la Apoptosis/genética; Proteínas Reguladoras de la Apoptosis/metabolismo; Linfocitos B/metabolismo; Linfocitos B/virología; Células Cultivadas; Herpesvirus Humano 4/genética; Herpesvirus Humano 4/metabolismo; Herpesvirus Humano 4/patogenicidad; Humanos; Lectinas Tipo C/genética; Lectinas Tipo C/metabolismo; Proteínas de la Membrana/genética; Proteínas de la Membrana/metabolismo; Esclerosis Múltiple/virología; Unión Proteica; Receptores Tipo I de Factores de Necrosis Tumoral/genética; Receptores Tipo I de Factores de Necrosis Tumoral/metabolismo; Factor 3 Asociado a Receptor de TNF/genética; Factor 3 Asociado a Receptor de TNF/metabolismo

Palabras clave

EBNA2; EBV; GWAS; MS; eQTL

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Antígenos Nucleares del Virus de Epstein-Barr / Esclerosis Múltiple Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Australia

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