Autophagy Dysfunction as a Phenotypic Readout in hiPSC-Derived Neuronal Cell Models of Neurodegenerative Diseases.

Sun, Congxin; Rosenstock, Tatiana R; Cohen, Malkiel A; Sarkar, Sovan

Sun, Congxin; Rosenstock, Tatiana R; Cohen, Malkiel A; Sarkar, Sovan.

Afiliación

Sun C; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Rosenstock TR; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Cohen MA; Department of Pharmacology, University of São Paulo, São Paulo, Brazil.
Sarkar S; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.

Methods Mol Biol ; 2549: 103-136, 2022.

Article en En | MEDLINE | ID: mdl-34490597

Asunto(s)

Células Madre Pluripotentes Inducidas; Enfermedades Neurodegenerativas; Autofagia; Homeostasis; Humanos; Células Madre Pluripotentes Inducidas/metabolismo; Enfermedades Neurodegenerativas/metabolismo; Neuronas/metabolismo

Palabras clave

Autophagosome; Autophagy; Autophagy dysfunction; Autophagy inducer; Autophagy substrate; Human induced pluripotent stem cells; LC3; Neurodegenerative disease; Neuronal differentiation; hiPSC-derived neurons; p62

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Neurodegenerativas / Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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