BRAF V600E Mediates Crizotinib Resistance and Responds to Dabrafenib and Trametinib in a ROS1-Rearranged Non-Small Cell Lung Cancer: A Case Report.

Li, Juan; Wang, Qifeng; Ge, Jun; Tian, Yuke; Yao, Wenxiu

Li, Juan; Wang, Qifeng; Ge, Jun; Tian, Yuke; Yao, Wenxiu.

Afiliación

Li J; Departments of Medical Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Wang Q; Departments of Thoracic Radiotherapy, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Ge J; Departments of Medical Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Tian Y; Departments of Medical Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.
Yao W; Departments of Medical Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.

Oncologist ; 26(12): e2115-e2119, 2021 12.

Article en En | MEDLINE | ID: mdl-34516041

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas; Neoplasias Pulmonares; Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Carcinoma de Pulmón de Células no Pequeñas/genética; Crizotinib/uso terapéutico; Resistencia a Antineoplásicos; Humanos; Imidazoles; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/genética; Oximas; Proteínas Tirosina Quinasas/genética; Proteínas Proto-Oncogénicas/genética; Proteínas Proto-Oncogénicas B-raf/genética; Piridonas; Pirimidinonas

Palabras clave

BRAF V600E; Crizotinib resistance; Dabrafenib and trametinib; Non-small cell lung cancer; ROS1 fusion

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Oncologist Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article

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