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Design, synthesis and anti-tumor evaluation of 1,2,4-triazol-3-one derivatives and pyridazinone derivatives as novel CXCR2 antagonists.
Zhang, Xun; Luo, Jingyi; Li, Qinyuan; Xin, Qilei; Ye, Lizhen; Zhu, Qingyun; Shi, Zhichao; Zhan, Feng; Chu, Bizhu; Liu, Zijian; Jiang, Yuyang.
Afiliación
  • Zhang X; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Luo J; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Li Q; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Xin Q; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Ye L; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Zhu Q; The First Affiliated Hospital, Department of Oncology, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.
  • Shi Z; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Zhan F; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China.
  • Chu B; School of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen, 518060, PR China.
  • Liu Z; Shenzhen Kivita Innovative Drug Discovery Institute, Shenzhen, 518057, PR China.
  • Jiang Y; Department of Chemistry, Tsinghua University, Beijing, 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China; Department of Pharmacology and Pharmaceutical
Eur J Med Chem ; 226: 113812, 2021 Dec 15.
Article en En | MEDLINE | ID: mdl-34536673
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridazinas / Triazoles / Diseño de Fármacos / Receptores de Interleucina-8B / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridazinas / Triazoles / Diseño de Fármacos / Receptores de Interleucina-8B / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article