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Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease.
Bénardeau, Agnès; Kahnert, Antje; Schomber, Tibor; Meyer, Jutta; Pavkovic, Mira; Kretschmer, Axel; Lawrenz, Bettina; Hartmann, Elke; Mathar, Ilka; Hueser, Joerg; Kraehling, Jan R; Eitner, Frank; Hahn, Michael G; Stasch, Johannes-Peter; Sandner, Peter.
Afiliación
  • Bénardeau A; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Kahnert A; Novo Nordisk, Bagsværd, Denmark.
  • Schomber T; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Meyer J; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Pavkovic M; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Kretschmer A; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Lawrenz B; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Hartmann E; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Mathar I; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Hueser J; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Kraehling JR; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Eitner F; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Hahn MG; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
  • Stasch JP; Division of Nephrology and Clinical Immunology, RWTH Aachen University, 52062, Aachen, Germany.
  • Sandner P; Cardiovascular Research, Pharma Research Center, Bayer AG, Aprather Weg 18A, 42096, Wuppertal, Germany.
Naunyn Schmiedebergs Arch Pharmacol ; 394(12): 2363-2379, 2021 12.
Article en En | MEDLINE | ID: mdl-34550407
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclopropanos / Diabetes Mellitus Experimental / Insuficiencia Renal Crónica / Hipertensión Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Naunyn Schmiedebergs Arch Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclopropanos / Diabetes Mellitus Experimental / Insuficiencia Renal Crónica / Hipertensión Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Naunyn Schmiedebergs Arch Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Alemania