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ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Ianniciello, Angela; Zarou, Martha M; Rattigan, Kevin M; Scott, Mary; Dawson, Amy; Dunn, Karen; Brabcova, Zuzana; Kalkman, Eric R; Nixon, Colin; Michie, Alison M; Copland, Mhairi; Vetrie, David; Ambler, Martin; Saxty, Barbara; Helgason, G Vignir.
Afiliación
  • Ianniciello A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Zarou MM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Rattigan KM; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Scott M; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Dawson A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Dunn K; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 0ZD, UK.
  • Brabcova Z; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Kalkman ER; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Nixon C; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Michie AM; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 0ZD, UK.
  • Copland M; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 0ZD, UK.
  • Vetrie D; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  • Ambler M; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, UK.
  • Saxty B; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, UK.
  • Helgason GV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
Sci Transl Med ; 13(613): eabd5016, 2021 Sep 29.
Article en En | MEDLINE | ID: mdl-34586834
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Estrés Oxidativo Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Estrés Oxidativo Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido