Clerodane Diterpenoids from an Edible Plant <i>Justicia insularis</i>: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells.

Fadayomi, Idowu E; Johnson-Ajinwo, Okiemute R; Pires, Elisabete; McCullagh, James; Claridge, Tim D W; Forsyth, Nicholas R; Li, Wen-Wu

Clerodane Diterpenoids from an Edible Plant Justicia insularis: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells.

Fadayomi, Idowu E; Johnson-Ajinwo, Okiemute R; Pires, Elisabete; McCullagh, James; Claridge, Tim D W; Forsyth, Nicholas R; Li, Wen-Wu.

Afiliación

Fadayomi IE; School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent ST4 7QB, UK.
Johnson-Ajinwo OR; School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent ST4 7QB, UK.
Pires E; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
McCullagh J; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
Claridge TDW; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
Forsyth NR; School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent ST4 7QB, UK.
Li WW; School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent ST4 7QB, UK.

Molecules ; 26(19)2021 Sep 30.

Article en En | MEDLINE | ID: mdl-34641476

Asunto(s)

Antineoplásicos Fitogénicos/farmacología; Diterpenos de Tipo Clerodano/farmacología; Género Justicia/química; Neoplasias Ováricas/tratamiento farmacológico; Extractos Vegetales/farmacología; Apoptosis/efectos de los fármacos; Descubrimiento de Drogas; Femenino; Humanos; Neoplasias Ováricas/patología; Hojas de la Planta/química; Células Tumorales Cultivadas

Palabras clave

Justicia insularis; cytotoxicity; diterpenoids; induction of apoptosis; ovarian cancer; target prediction

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Extractos Vegetales / Género Justicia / Diterpenos de Tipo Clerodano / Antineoplásicos Fitogénicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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