CYLD destabilizes NoxO1 protein by promoting ubiquitination and regulates prostate cancer progression.

Haq, Saba; Sarodaya, Neha; Karapurkar, Janardhan Keshav; Suresh, Bharathi; Jo, Jung Ki; Singh, Vijai; Bae, Yun Soo; Kim, Kye-Seong; Ramakrishna, Suresh

Haq, Saba; Sarodaya, Neha; Karapurkar, Janardhan Keshav; Suresh, Bharathi; Jo, Jung Ki; Singh, Vijai; Bae, Yun Soo; Kim, Kye-Seong; Ramakrishna, Suresh.

Afiliación

Haq S; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, 04763, South Korea.
Sarodaya N; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea.
Karapurkar JK; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea.
Suresh B; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea.
Jo JK; Department of Urology, Hanyang University College of Medicine, Seoul, 04763, South Korea.
Singh V; Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, Gujarat, India.
Bae YS; Department of Life Science, Ewha Womans University, Seoul, South Korea.
Kim KS; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea; College of Medicine, Hanyang University, Seoul, 04763, South Korea. Electronic address: ks66kim@hanyang.ac.kr.
Ramakrishna S; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea; College of Medicine, Hanyang University, Seoul, 04763, South Korea. Electronic address: suri28@hanyang.ac.kr.

Cancer Lett ; 525: 146-157, 2022 01 28.

Article en En | MEDLINE | ID: mdl-34742871

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/genética; Enzima Desubiquitinante CYLD/genética; Neoplasias de la Próstata/genética; Ubiquitinación/genética; Animales; Apoptosis/genética; Sistemas CRISPR-Cas/genética; Proliferación Celular/genética; Enzimas Desubicuitinizantes/genética; Progresión de la Enfermedad; Regulación Neoplásica de la Expresión Génica/genética; Genoma Humano/genética; Xenoinjertos; Humanos; Masculino; Neoplasias de la Próstata/patología; Especies Reactivas de Oxígeno/metabolismo; Transducción de Señal/genética

Palabras clave

CRISPR/Cas9; Colon cancer; Deubiquitination; Proteasomal degradation; Proteolysis; ROS

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Proteínas Adaptadoras Transductoras de Señales / Ubiquitinación / Enzima Desubiquitinante CYLD Límite: Animals / Humans / Male Idioma: En Revista: Cancer Lett Año: 2022 Tipo del documento: Article País de afiliación: Corea del Sur

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