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Rare missense variants in Tropomyosin-4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects, and excessive bleeding.
Stapley, Rachel J; Poulter, Natalie S; Khan, Abdullah O; Smith, Christopher W; Bignell, Patricia; Fratter, Carl; Lester, Will; Lowe, Gillian; Morgan, Neil V.
Afiliación
  • Stapley RJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Poulter NS; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Khan AO; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands, UK.
  • Smith CW; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Bignell P; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Fratter C; Oxford Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Lester W; Oxford Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Lowe G; Comprehensive Care Haemophilia Centre, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
  • Morgan NV; Comprehensive Care Haemophilia Centre, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
J Thromb Haemost ; 20(2): 478-485, 2022 02.
Article en En | MEDLINE | ID: mdl-34758189
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trombocitopenia / Trastornos de las Plaquetas Sanguíneas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Thromb Haemost Asunto de la revista: HEMATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trombocitopenia / Trastornos de las Plaquetas Sanguíneas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Thromb Haemost Asunto de la revista: HEMATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido