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Chronic pharmacological antagonism of the GM-CSF receptor in mice does not replicate the pulmonary alveolar proteinosis phenotype but does alter lung surfactant turnover.
Corkill, Dominic J; Hunt, Alan N; Hinrichs, Mary Jane; White, Nicholas; Rebelatto, Marlon; Roskos, Lorin; Nys, Josquin; Scott, Alison; Robinson, Matthew J; Ryan, Patricia; Postle, Anthony D; Sleeman, Matthew A.
Afiliación
  • Corkill DJ; Research and Early Development, Respiratory & Immunology (R&I), AstraZeneca, Cambridge, U.K.
  • Hunt AN; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, U.K.
  • Hinrichs MJ; Biologics Safety Assessment, AstraZeneca, Gaithersburg, MD, U.S.A.
  • White N; Bioanalytical Sciences, AstraZeneca, Cambridge, U.K.
  • Rebelatto M; Biologics Safety Assessment, AstraZeneca, Gaithersburg, MD, U.S.A.
  • Roskos L; Biologics Safety Assessment, AstraZeneca, Gaithersburg, MD, U.S.A.
  • Nys J; Research and Early Development, Respiratory & Immunology (R&I), AstraZeneca, Cambridge, U.K.
  • Scott A; Biologics Safety Assessment, AstraZeneca, Cambridge, U.K.
  • Robinson MJ; Research and Early Development, Respiratory & Immunology (R&I), AstraZeneca, Cambridge, U.K.
  • Ryan P; Biologics Safety Assessment, AstraZeneca, Gaithersburg, MD, U.S.A.
  • Postle AD; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, U.K.
  • Sleeman MA; Research and Early Development, Respiratory & Immunology (R&I), AstraZeneca, Cambridge, U.K.
Clin Sci (Lond) ; 135(22): 2559-2573, 2021 11 26.
Article en En | MEDLINE | ID: mdl-34778899
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Proteinosis Alveolar Pulmonar / Surfactantes Pulmonares / Receptores de Factor Estimulante de Colonias de Granulocitos y Macrófagos / COVID-19 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Clin Sci (Lond) Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Proteinosis Alveolar Pulmonar / Surfactantes Pulmonares / Receptores de Factor Estimulante de Colonias de Granulocitos y Macrófagos / COVID-19 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Clin Sci (Lond) Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido