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Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine.
Gebre, Makda S; Rauch, Susanne; Roth, Nicole; Yu, Jingyou; Chandrashekar, Abishek; Mercado, Noe B; He, Xuan; Liu, Jinyan; McMahan, Katherine; Martinot, Amanda; Martinez, David R; Giffin, Victoria; Hope, David; Patel, Shivani; Sellers, Daniel; Sanborn, Owen; Barrett, Julia; Liu, Xiaowen; Cole, Andrew C; Pessaint, Laurent; Valentin, Daniel; Flinchbaugh, Zack; Yalley-Ogunro, Jake; Muench, Jeanne; Brown, Renita; Cook, Anthony; Teow, Elyse; Andersen, Hanne; Lewis, Mark G; Boon, Adrianus C M; Baric, Ralph S; Mueller, Stefan O; Petsch, Benjamin; Barouch, Dan H.
Afiliación
  • Gebre MS; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Rauch S; CureVac AG, Tübingen, Germany. Susanne.rauch@curevac.com.
  • Roth N; CureVac AG, Tübingen, Germany.
  • Yu J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Chandrashekar A; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Mercado NB; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • He X; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Liu J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • McMahan K; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Martinot A; Tufts University Cummings School of Veterinary Medicine, North Grafton, MA, USA.
  • Martinez DR; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Giffin V; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Hope D; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Patel S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Sellers D; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Sanborn O; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Barrett J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Liu X; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Cole AC; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Pessaint L; Bioqual, Rockville, MD, USA.
  • Valentin D; Bioqual, Rockville, MD, USA.
  • Flinchbaugh Z; Bioqual, Rockville, MD, USA.
  • Yalley-Ogunro J; Bioqual, Rockville, MD, USA.
  • Muench J; Bioqual, Rockville, MD, USA.
  • Brown R; Bioqual, Rockville, MD, USA.
  • Cook A; Bioqual, Rockville, MD, USA.
  • Teow E; Bioqual, Rockville, MD, USA.
  • Andersen H; Bioqual, Rockville, MD, USA.
  • Lewis MG; Bioqual, Rockville, MD, USA.
  • Boon ACM; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Baric RS; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Mueller SO; CureVac AG, Tübingen, Germany.
  • Petsch B; CureVac AG, Tübingen, Germany.
  • Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. dbarouch@bidmc.harvard.edu.
Nature ; 601(7893): 410-414, 2022 01.
Article en En | MEDLINE | ID: mdl-34794169

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Sintéticas / Inmunogenicidad Vacunal / Vacunas contra la COVID-19 / COVID-19 / Vacunas de ARNm / Nucleósidos Límite: Animals Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Sintéticas / Inmunogenicidad Vacunal / Vacunas contra la COVID-19 / COVID-19 / Vacunas de ARNm / Nucleósidos Límite: Animals Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos