Towards precise large genomic fragment deletion.

Li, Xiangyang; Huang, Xingxu

Li, Xiangyang; Huang, Xingxu.

Afiliación

Li X; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Huang X; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou 310029, China. Electronic address: huangxx@shanghaitech.edu.cn.

Trends Genet ; 38(3): 214-215, 2022 03.

Article en En | MEDLINE | ID: mdl-34872747

RESUMEN

The prime editing (PE) system can install small insertions and deletions in addition to various base substitutions. Two recent studies published in Nature Biotechnology by Choi et al. and Jiang et al. report that the system can also be tweaked for efficient and precise deletions of large DNA fragments.

Asunto(s)

Sistemas CRISPR-Cas; Edición Génica; Sistemas CRISPR-Cas/genética; ADN/genética; Genoma/genética; Genómica

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Idioma: En Revista: Trends Genet Asunto de la revista: GENETICA Año: 2022 Tipo del documento: Article País de afiliación: China

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