Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress.
J Adv Res
; 34: 43-63, 2021 12.
Article
en En
| MEDLINE
| ID: mdl-35024180
Palabras clave
7-HMR, (−)-7(S)-hydroxymatairesinol; ADH, andrographolide; AGE, advanced glycation end product; AMP, Athyrium Multidentatum; APV, aqueous extracts of Prunella Vulgaris; ARE, antioxidant reaction elements; AS, atherosclerosis; ASD-IV, Astragaloside IV; ASP, Angelica sinensis polysaccharide; ASTP, Astragalus polysacharin; Akt, protein kinase B; Ang, Angiotensin; ApoE, apolipoprotein E; Atherosclerosis; BAECs, bovine artery endothelial cells; BBR, Berberine; BITC, benzyl isothiocyanate; C3G, Cyanidin-3-O-glucoside; CINM, Cinnamaldehyde; CNC, Cap'n'collar; CREB, cAMP-response element binding protein; CVDs, cardiovascular diseases; CVRF, cardiovascular risk factors; DMY, Dihydromyricetin; ECC, (−)-Epicatechin; ECs, endothelial cells; EGCG, epigallocatechin-3-O-gallate; ERK, extracellular regulated protein kinases; ET, endothelin; EXS, Xanthoceras sorbifolia; FFA, Fatty Acids; GPx, Glutathione peroxidase; GSD Rg1, Ginsenoside Rg1; GTE, Ganoderma tsugae extracts; Gau A, Glaucocalyxin A; HAMS, human anthocyanin medicated serum; HG, high glucose; HIF-1, Hypoxia-inducible factor 1; HO-1, heme oxygenase; HUVECs, human umbilical vein endothelial cells; HXC, Huoxue capsule; Hcy, Homocysteine; Herbal medicine; ICAM, intercellular adhesion molecule; IL, interleukin; KGRE, extracts of KGR; KRG, Korean red ginseng; Keap1, kelch-like epichlorohydrin-related proteins; LWDH, Liuwei-Dihuang pill; MA, maslinic acid; MAPKK, mitogen-activated protein kinase kinase; MAPKs, mitogen-activated protein kinases; MCGA3, 3-O-caffeoyl-1-methylquinic acid; MCP-1, monocyte chemotactic protein 1; MMPs, matrix metalloproteinases; Molecular mechanism; NAF, Nepeta Angustifolia; NF-κB, nuclear factor kappa-B; NG, naringenin; NQO1, NAD(P)H: quinone oxidoreductase; Nrf2, nuclear factor erythroid-2 related factor 2; Nrf2/HO-1 signaling; OA, Oleanolic acid; OMT, Oxymatrine; OX-LDL, oxidized low density lipoprotein; Oxidative stress; PA, Palmitate; PAA, Pachymic acid; PAI-1, plasminogen activator Inhibitor-1; PEITC, phenethyl isocyanate; PI3K, phosphatidylinositol 3 kinase; PKC, protein kinase C; PT, Pterostilbene; RBPC, phenolic extracts derived from rice bran; ROS, reactive oxygen species; SAL, Salidroside; SFN, sulforaphane; SMT, Samul-Tang Tang; SOD, superoxide dismutase; Sal B, salvianolic acid B; SchB, Schisandrin B; TCM, traditional Chinese medicine; TNF, tumor necrosis factor; TXA2, Thromboxane A2; TrxR1, thioredoxin reductase-1; US, uraemic serum; VA, Vanillic acid; VCAM, vascular cell adhesion molecule; VEC, vascular endothelial cells; VEI, vascular endothelial injury; Vascular endothelial cells; XAG, xanthoangelol; XXT, Xueshuan Xinmaining Tablet; Z-Lig, Z-ligustilide; eNOS, endothelial NO synthase
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Preparaciones Farmacéuticas
/
Aterosclerosis
Tipo de estudio:
Risk_factors_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
J Adv Res
Año:
2021
Tipo del documento:
Article