Stimulation of the methylation pathway for phosphatidylcholine synthesis in rat lungs by choline deficiency.
Biochim Biophys Acta
; 875(1): 122-5, 1986 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-3510063
ABSTRACT
The methylation of phosphatidylethanolamine (PE) to form phosphatidylcholine (PC) was investigated using the isolated rat lung perfused with radiolabeled ethanolamine. Lungs from choline-deficient rats showed increased incorporation of radiolabel into PC at 2 h of perfusion. Increased PC synthesis from PE was also observed with lungs from rats fed a lipotrophic (choline plus methionine deficient) diet when methionine was added to the lung perfusate. These results indicate increased activity of the methylation pathway for lung PC synthesis during choline deficiency.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fosfatidilcolinas
/
Deficiencia de Colina
/
Pulmón
Límite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
1986
Tipo del documento:
Article