Local Accumulation of Lymphocytes in the Intima of Human Aorta Is Associated with Giant Multinucleated Endothelial Cells: Possible Explanation for Mosaicism of Atherosclerosis.

Nikiforov, Nikita G; Zlenko, Dmitry V; Orekhova, Varvara A; Melnichenko, Alexandra A; Orekhov, Alexander N

Nikiforov, Nikita G; Zlenko, Dmitry V; Orekhova, Varvara A; Melnichenko, Alexandra A; Orekhov, Alexander N.

Afiliación

Nikiforov NG; Laboratory of Medical Genetics, Institute of Experimental Cardiology, National Medical Research Center of Cardiology, 121552 Moscow, Russia.
Zlenko DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Orekhova VA; Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Melnichenko AA; N.N. Semenov Federal Research Center for Chemical Physics RAS, 119991 Moscow, Russia.
Orekhov AN; Faculty of Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.

Int J Mol Sci ; 23(3)2022 Jan 19.

Article en En | MEDLINE | ID: mdl-35162983

Asunto(s)

Aterosclerosis; Células Endoteliales; Adulto; Aorta/patología; Aterosclerosis/patología; Células Endoteliales/patología; Endotelio Vascular/patología; Humanos; Lipoproteínas LDL; Linfocitos/patología; Persona de Mediana Edad; Mosaicismo; Adulto Joven

Palabras clave

LDL; aortic intima; atherosclerosis; giant multinuclear endothelial cells; leukocytes; mosaicism

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Endoteliales / Aterosclerosis Tipo de estudio: Risk_factors_studies Límite: Adult / Humans / Middle aged Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Rusia

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