Selected Histone Deacetylase Inhibitors Reverse the Frataxin Transcriptional Defect in a Novel Friedreich's Ataxia Induced Pluripotent Stem Cell-Derived Neuronal Reporter System.

Schreiber, Anna M; Li, Yanjie; Chen, Yi-Hsien; Napierala, Jill S; Napierala, Marek

Schreiber, Anna M; Li, Yanjie; Chen, Yi-Hsien; Napierala, Jill S; Napierala, Marek.

Afiliación

Schreiber AM; Department of Biochemistry and Molecular Genetics, Stem Cell Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
Li Y; Department of Biochemistry and Molecular Genetics, Stem Cell Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
Chen YH; Genome Engineering and iPSC Center, Washington University, St. Louis, MO, United States.
Napierala JS; Department of Biochemistry and Molecular Genetics, Stem Cell Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
Napierala M; Department of Biochemistry and Molecular Genetics, Stem Cell Institute, University of Alabama at Birmingham, Birmingham, AL, United States.

Front Neurosci ; 16: 836476, 2022.

Article en En | MEDLINE | ID: mdl-35281493

Palabras clave

Friedreich's ataxia (FRDA); Nanoluciferase; induced pluripotent stem cells; neural progenitor cells (NPCs); reporter cell line; screening

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Front Neurosci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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