B-cell activating factor and IL-21 levels predict treatment response in autoimmune hepatitis.

Biewenga, Maaike; Heidt, Sebastiaan; Vergunst, Manon; Marijnissen, Camiel M J; de Man, Rob A; van der Eijk, Annemiek A; van der Meer, Adriaan J; Trouw, Leendert A; van Hoek, Bart

Biewenga, Maaike; Heidt, Sebastiaan; Vergunst, Manon; Marijnissen, Camiel M J; de Man, Rob A; van der Eijk, Annemiek A; van der Meer, Adriaan J; Trouw, Leendert A; van Hoek, Bart.

Afiliación

Biewenga M; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
Heidt S; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
Vergunst M; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
Marijnissen CMJ; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
de Man RA; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands.
van der Eijk AA; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
van der Meer AJ; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
van Hoek B; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.

JHEP Rep ; 4(5): 100460, 2022 May.

Article en En | MEDLINE | ID: mdl-35368991

Palabras clave

AIH, autoimmune hepatitis; ALT, alanine aminotransferase; AP, alkaline phosphatase; AST, aspartate aminotransferase; Autoimmune hepatitis; B-cell immunity; BAFF; BAFF, B-cell activating factor of the tumour necrosis family; Biochemical remission; GGT, gamma-glutamyltransferase; IL-21; LKM-1, liverkidneymicrosomal type 1; MRCP, magnetic resonance cholangiopancreaticography; PBC, primary biliary cholangitis; PBMC, peripheral blood mononuclear cell; PSC, primary sclerosing cholangitis; UDCA, ursodeoxycholic acid; ULN, upper limit of normal

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: JHEP Rep Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos

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