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Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins.
Yunes, Sarah A; Willoughby, Jennifer L S; Kwan, Julian H; Biagi, Jessica M; Pokharel, Niranjana; Chin, Hang Gyeong; York, Emily A; Su, Kuan-Chung; George, Kelly; Shah, Jagesh V; Emili, Andrew; Schaus, Scott E; Hansen, Ulla.
Afiliación
  • Yunes SA; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • Willoughby JLS; Program in Molecular Biology, Cell Biology, and Biochemistry, Boston University, Boston, Massachusetts, United States of America.
  • Kwan JH; Program in Molecular Biology, Cell Biology, and Biochemistry, Boston University, Boston, Massachusetts, United States of America.
  • Biagi JM; Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America.
  • Pokharel N; Department of Biochemistry and Center for Network Systems Biology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
  • Chin HG; Department of Chemistry and Center for Molecular Discovery, Boston University, Boston, Massachusetts, United States of America.
  • York EA; Department of Chemistry and Center for Molecular Discovery, Boston University, Boston, Massachusetts, United States of America.
  • Su KC; Program in Molecular Biology, Cell Biology, and Biochemistry, Boston University, Boston, Massachusetts, United States of America.
  • George K; New England Biolabs, Ipswich, Massachusetts, United States of America.
  • Shah JV; Department of Chemistry and Center for Molecular Discovery, Boston University, Boston, Massachusetts, United States of America.
  • Emili A; Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America.
  • Schaus SE; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Hansen U; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America.
PLoS One ; 17(6): e0268857, 2022.
Article en En | MEDLINE | ID: mdl-35704642
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinolonas / Proteínas Asociadas a Microtúbulos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinolonas / Proteínas Asociadas a Microtúbulos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos