Guinea pig pancreatic polypeptide: structure and pancreatic content.
Peptides
; 8(1): 165-8, 1987.
Article
en En
| MEDLINE
| ID: mdl-3575148
ABSTRACT
Guinea pig (GP) pancreatic polypeptide (PP) has been purified from an acid-alcohol extract of 6 GP pancreata by a series of 3 HPLC steps. The sequence for GP PP as compared with that of beef and human is shown (Sequence see text). In a single GP pancreas weighing 2.4 g the total PP content was 1.0 nmol and the total glucagon content 61 nmol; in a single dog pancreas weighing 35 g the total PP was 385 nmol and the total glucagon 81 nmol. The relatively low content of PP in GP pancreas is consistent with the fact that the GP lacks a ventral pancreas, the region in which PP is found in highest concentration. The high glucagon content of GP pancreas is consistent with that reported in earlier studies.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Páncreas
/
Polipéptido Pancreático
Límite:
Animals
Idioma:
En
Revista:
Peptides
Año:
1987
Tipo del documento:
Article