Structural Basis of the Pancreatitis-Associated Autoproteolytic Failsafe Mechanism in Human Anionic Trypsin.

Nagel, Felix; Susemihl, Anne; Geist, Norman; Möhlis, Kevin; Palm, Gottfried J; Lammers, Michael; Delcea, Mihaela

Nagel, Felix; Susemihl, Anne; Geist, Norman; Möhlis, Kevin; Palm, Gottfried J; Lammers, Michael; Delcea, Mihaela.

Afiliación

Nagel F; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Susemihl A; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Geist N; Department of Hematology and Oncology, Internal Medicine C, University of Greifswald, Greifswald, Germany.
Möhlis K; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Palm GJ; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.
Lammers M; Helmholtz Institute for Metabolic, Obesity and Vascular Research, Leipzig, Germany.
Delcea M; Synthetic and Structural Biochemistry, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.

J Inflamm Res ; 15: 3633-3642, 2022.

Article en En | MEDLINE | ID: mdl-35775010

Palabras clave

R122H; autoproteolysis; crystal structure; pancreas; pancreatitis; serine protease

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: J Inflamm Res Año: 2022 Tipo del documento: Article País de afiliación: Alemania

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