Targeting the Achilles' Heel of Multidrug-Resistant <i>Staphylococcus aureus</i> by the Endocannabinoid Anandamide.

Sionov, Ronit Vogt; Banerjee, Shreya; Bogomolov, Sergei; Smoum, Reem; Mechoulam, Raphael; Steinberg, Doron

Targeting the Achilles' Heel of Multidrug-Resistant Staphylococcus aureus by the Endocannabinoid Anandamide.

Sionov, Ronit Vogt; Banerjee, Shreya; Bogomolov, Sergei; Smoum, Reem; Mechoulam, Raphael; Steinberg, Doron.

Afiliación

Sionov RV; Biofilm Research Laboratory, Institute of Biomedical and Oral Sciences, Faculty of Dentistry, Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Banerjee S; Biofilm Research Laboratory, Institute of Biomedical and Oral Sciences, Faculty of Dentistry, Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Bogomolov S; Biofilm Research Laboratory, Institute of Biomedical and Oral Sciences, Faculty of Dentistry, Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Smoum R; Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Mechoulam R; Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Steinberg D; Biofilm Research Laboratory, Institute of Biomedical and Oral Sciences, Faculty of Dentistry, Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.

Int J Mol Sci ; 23(14)2022 Jul 14.

Article en En | MEDLINE | ID: mdl-35887146

Asunto(s)

Fenómenos Bioquímicos; Staphylococcus aureus Resistente a Meticilina; Infecciones Estafilocócicas; Antibacterianos/farmacología; Antibacterianos/uso terapéutico; Ácidos Araquidónicos; Endocannabinoides/metabolismo; Endocannabinoides/farmacología; GTP Fosfohidrolasas/metabolismo; Humanos; Staphylococcus aureus Resistente a Meticilina/metabolismo; Alcamidas Poliinsaturadas/metabolismo; Infecciones Estafilocócicas/tratamiento farmacológico; Staphylococcus aureus/metabolismo

Palabras clave

Staphylococcus aureus; anandamide; antibiotic resistance; autolysins; drug sensitization; endocannabinoids; transmembrane transport; wall teichoic acid

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Fenómenos Bioquímicos / Staphylococcus aureus Resistente a Meticilina Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Israel

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