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Diamond-Blackfan anaemia with iron overload: A serious issue.
Quarello, Paola; Ramenghi, Ugo; Fagioli, Franca.
Afiliación
  • Quarello P; Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Azienda Ospedaliera-Universitaria Città della Salute e della Scienza, University of Torino, Torino, Italy.
  • Ramenghi U; Department of Pediatric and Public Health Sciences, University of Turin, Turin, Italy.
  • Fagioli F; Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Azienda Ospedaliera-Universitaria Città della Salute e della Scienza, University of Torino, Torino, Italy.
Br J Haematol ; 199(2): 171-172, 2022 10.
Article en En | MEDLINE | ID: mdl-35929529
Transfusion-dependent Diamond-Blackfan anaemia (DBA) patients rapidly develop iron overload and frequently experience cardiac complications. The report by Lecornec and colleagues offers useful details on indications and the management of deferiprone, a highly efficient chelator in removing excess cardiac iron but associated with a high risk of agranulocytosis in DBA patients. Commentary on: Lecornec et al. Agranulocytosis in patients with Diamond-Blackfan anaemia (DBA) treated with deferiprone for post-transfusion iron overload: A retrospective study of the French DBA cohort. British Journal of Haematology 2022;199:285-288.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sobrecarga de Hierro / Anemia de Diamond-Blackfan / Agranulocitosis Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Br J Haematol Año: 2022 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sobrecarga de Hierro / Anemia de Diamond-Blackfan / Agranulocitosis Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Br J Haematol Año: 2022 Tipo del documento: Article País de afiliación: Italia