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Discovery of compounds that reactivate p53 mutants in vitro and in vivo.
Durairaj, Geetha; Demir, Özlem; Lim, Bryant; Baronio, Roberta; Tifrea, Delia; Hall, Linda V; DeForest, Jacob C; Lauinger, Linda; Jebril Fallatah, Maryam M; Yu, Clinton; Bae, Hosung; Lin, Da-Wei; Kim, Jin Kwang; Salehi, Faezeh; Jang, Cholsoon; Qiao, Feng; Lathrop, Richard H; Huang, Lan; Edwards, Robert; Rychnovsky, Scott; Amaro, Rommie E; Kaiser, Peter.
Afiliación
  • Durairaj G; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA 92697, USA.
  • Demir Ö; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
  • Lim B; Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Baronio R; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Tifrea D; Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  • Hall LV; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • DeForest JC; Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Lauinger L; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Jebril Fallatah MM; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Yu C; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92697, USA; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.
  • Bae H; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Lin DW; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Kim JK; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Salehi F; Department of Computer Science, University of California, Irvine, Irvine, CA 92697, USA.
  • Jang C; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Qiao F; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Lathrop RH; Department of Computer Science, University of California, Irvine, Irvine, CA 92697, USA; Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA.
  • Huang L; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92697, USA; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.
  • Edwards R; Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  • Rychnovsky S; Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Amaro RE; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: ramaro@ucsd.edu.
  • Kaiser P; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA 92697, USA. Electronic address: pkaiser@uci.edu.
Cell Chem Biol ; 29(9): 1381-1395.e13, 2022 09 15.
Article en En | MEDLINE | ID: mdl-35948006
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Neoplasias Límite: Humans Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Neoplasias Límite: Humans Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos