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Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models.
Rossotti, Martin A; van Faassen, Henk; Tran, Anh T; Sheff, Joey; Sandhu, Jagdeep K; Duque, Diana; Hewitt, Melissa; Wen, Xiaoxue; Bavananthasivam, Jegarubee; Beitari, Saina; Matte, Kevin; Laroche, Geneviève; Giguère, Patrick M; Gervais, Christian; Stuible, Matthew; Guimond, Julie; Perret, Sylvie; Hussack, Greg; Langlois, Marc-André; Durocher, Yves; Tanha, Jamshid.
Afiliación
  • Rossotti MA; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • van Faassen H; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Tran AT; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Sheff J; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Sandhu JK; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Duque D; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Hewitt M; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Wen X; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Bavananthasivam J; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Beitari S; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Matte K; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Laroche G; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Giguère PM; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Gervais C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Stuible M; University of Ottawa Brain and Mind Research Institute, University of Ottawa, Ottawa, ON, Canada.
  • Guimond J; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Montréal, QC, Canada.
  • Perret S; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Montréal, QC, Canada.
  • Hussack G; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Montréal, QC, Canada.
  • Langlois MA; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Montréal, QC, Canada.
  • Durocher Y; Human Health Therapeutics Research Centre, Life Sciences Division, National Research Council Canada, Ottawa, ON, Canada.
  • Tanha J; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Commun Biol ; 5(1): 933, 2022 09 09.
Article en En | MEDLINE | ID: mdl-36085335
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Anticuerpos de Dominio Único / COVID-19 Límite: Animals / Humans Idioma: En Revista: Commun Biol Año: 2022 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Anticuerpos de Dominio Único / COVID-19 Límite: Animals / Humans Idioma: En Revista: Commun Biol Año: 2022 Tipo del documento: Article País de afiliación: Canadá