Heilaohuacid G, a new triterpenoid from Kadsura coccinea inhibits proliferation, induces apoptosis, and ameliorates inflammation in RA-FLS and RAW 264.7 cells via suppressing NF-ðB pathway.

Yang, Yu-Pei; Jian, Yu-Qing; Liu, Yong-Bei; Xie, Qing-Ling; Yu, Huang-He; Wang, Bin; Li, Bin; Peng, Cai-Yun; Wang, Wei

Heilaohuacid G, a new triterpenoid from Kadsura coccinea inhibits proliferation, induces apoptosis, and ameliorates inflammation in RA-FLS and RAW 264.7 cells via suppressing NF-ðB pathway.

Yang, Yu-Pei; Jian, Yu-Qing; Liu, Yong-Bei; Xie, Qing-Ling; Yu, Huang-He; Wang, Bin; Li, Bin; Peng, Cai-Yun; Wang, Wei.

Afiliación

Yang YP; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Jian YQ; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Liu YB; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Xie QL; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Yu HH; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Wang B; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Li B; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Peng CY; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.
Wang W; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, People's Republic of China.

Phytother Res ; 36(10): 3900-3910, 2022 Oct.

Article en En | MEDLINE | ID: mdl-36104304

Asunto(s)

Artritis Reumatoide; Kadsura; Osteoartritis; Fiebre Reumática; Triterpenos; Animales; Apoptosis; Artritis Reumatoide/tratamiento farmacológico; Artritis Reumatoide/metabolismo; Proliferación Celular; Células Cultivadas; Citocinas/metabolismo; Etanol/farmacología; Fibroblastos/metabolismo; Inflamación/tratamiento farmacológico; Inflamación/metabolismo; Lipopolisacáridos/farmacología; Ratones; FN-kappa B/metabolismo; Extractos Vegetales/uso terapéutico; Células RAW 264.7; Fiebre Reumática/metabolismo; Membrana Sinovial; Triterpenos/farmacología; Triterpenos/uso terapéutico; Xilenos/metabolismo; Xilenos/farmacología; Xilenos/uso terapéutico

Palabras clave

Heilaohu; Kadsura coccinea; Rheumatoid arthritis; Schisandraceae; Triterpenoid; Tujia ethnomedicine

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Artritis Reumatoide / Fiebre Reumática / Triterpenos / Kadsura Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Phytother Res Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2022 Tipo del documento: Article

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