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Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Yang, Kailu; Wang, Chuchu; Kreutzberger, Alex J B; Ojha, Ravi; Kuivanen, Suvi; Couoh-Cardel, Sergio; Muratcioglu, Serena; Eisen, Timothy J; White, K Ian; Held, Richard G; Subramanian, Subu; Marcus, Kendra; Pfuetzner, Richard A; Esquivies, Luis; Doyle, Catherine A; Kuriyan, John; Vapalahti, Olli; Balistreri, Giuseppe; Kirchhausen, Tom; Brunger, Axel T.
Afiliación
  • Yang K; HHMI, Stanford University, Stanford, CA 94305.
  • Wang C; Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305.
  • Kreutzberger AJB; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305.
  • Ojha R; Department of Structural Biology, Stanford University, Stanford, CA 94305.
  • Kuivanen S; Department of Photon Science, Stanford University, Stanford, CA 94305.
  • Couoh-Cardel S; HHMI, Stanford University, Stanford, CA 94305.
  • Muratcioglu S; Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305.
  • Eisen TJ; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305.
  • White KI; Department of Structural Biology, Stanford University, Stanford, CA 94305.
  • Held RG; Department of Photon Science, Stanford University, Stanford, CA 94305.
  • Subramanian S; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Marcus K; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
  • Pfuetzner RA; Department of Virology, University of Helsinki, Helsinki 00290, Finland.
  • Esquivies L; Department of Virology, University of Helsinki, Helsinki 00290, Finland.
  • Doyle CA; HHMI, Stanford University, Stanford, CA 94305.
  • Kuriyan J; Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305.
  • Vapalahti O; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305.
  • Balistreri G; Department of Structural Biology, Stanford University, Stanford, CA 94305.
  • Kirchhausen T; Department of Photon Science, Stanford University, Stanford, CA 94305.
  • Brunger AT; HHMI, University of California, Berkeley, Berkeley, CA 94720.
Proc Natl Acad Sci U S A ; 119(40): e2210990119, 2022 10 04.
Article en En | MEDLINE | ID: mdl-36122200
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glicoproteína de la Espiga del Coronavirus / Tratamiento Farmacológico de COVID-19 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glicoproteína de la Espiga del Coronavirus / Tratamiento Farmacológico de COVID-19 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article