Editing human hematopoietic stem cells: advances and challenges.

Bhoopalan, Senthil Velan; Yen, Jonathan S; Levine, Rachel M; Sharma, Akshay

Bhoopalan, Senthil Velan; Yen, Jonathan S; Levine, Rachel M; Sharma, Akshay.

Afiliación

Bhoopalan SV; Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Yen JS; Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Levine RM; Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Sharma A; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: akshay.sharma@stjude.org.

Cytotherapy ; 25(3): 261-269, 2023 03.

Article en En | MEDLINE | ID: mdl-36123234

Asunto(s)

Sistemas CRISPR-Cas; Células Madre Hematopoyéticas; Humanos; Sistemas CRISPR-Cas/genética; Edición Génica/métodos; Terapia Genética/métodos

Palabras clave

CRISPR-Cas9; hematopoietic stem cells; severe congenital neutropenia; sickle cell disease

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Sistemas CRISPR-Cas Límite: Humans Idioma: En Revista: Cytotherapy Asunto de la revista: TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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