The 1,2,3-triazole 'all-in-one' ring system in drug discovery: a good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool.

Lengerli, Deniz; Ibis, Kübra; Nural, Yahya; Banoglu, Erden

Lengerli, Deniz; Ibis, Kübra; Nural, Yahya; Banoglu, Erden.

Afiliación

Lengerli D; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey.
Ibis K; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey.
Nural Y; Department of Analytical Chemistry, Faculty of Pharmacy, Mersin University, Mersin, Turkey.
Banoglu E; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey.

Expert Opin Drug Discov ; 17(11): 1209-1236, 2022 11.

Article en En | MEDLINE | ID: mdl-36164263

Asunto(s)

Farmacóforo; Triazoles; Humanos; Triazoles/farmacología; Triazoles/química; Química Clic; Descubrimiento de Drogas; Química Farmacéutica

Palabras clave

1; 2; 3-triazole; bioisostere; linker; pharmacophore; synthetic tool

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triazoles / Farmacóforo Límite: Humans Idioma: En Revista: Expert Opin Drug Discov Año: 2022 Tipo del documento: Article País de afiliación: Turquía

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