Enhanced neutralization potency of an identical HIV neutralizing antibody expressed as different isotypes is achieved through genetically distinct mechanisms.

Moyo-Gwete, Thandeka; Scheepers, Cathrine; Makhado, Zanele; Kgagudi, Prudence; Mzindle, Nonkululeko B; Ziki, Rutendo; Madzorera, Sharon; Manamela, Nelia P; Ayres, Frances; Lambson, Bronwen E; Richardson, Simone I; Morris, Lynn; Moore, Penny L

Moyo-Gwete, Thandeka; Scheepers, Cathrine; Makhado, Zanele; Kgagudi, Prudence; Mzindle, Nonkululeko B; Ziki, Rutendo; Madzorera, Sharon; Manamela, Nelia P; Ayres, Frances; Lambson, Bronwen E; Richardson, Simone I; Morris, Lynn; Moore, Penny L.

Afiliación

Moyo-Gwete T; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.
Scheepers C; SA MRC Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Makhado Z; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.
Kgagudi P; SA MRC Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Mzindle NB; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.
Ziki R; SA MRC Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Madzorera S; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.
Manamela NP; SA MRC Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Ayres F; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.
Lambson BE; SA MRC Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Richardson SI; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.
Morris L; SA MRC Antibody Immunity Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Moore PL; Centre for HIV and STIs, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

Sci Rep ; 12(1): 16473, 2022 10 01.

Article en En | MEDLINE | ID: mdl-36182959

Asunto(s)

Infecciones por VIH; VIH-1; Anticuerpos Monoclonales; Anticuerpos Neutralizantes; Citotoxicidad Celular Dependiente de Anticuerpos; Anticuerpos Anti-VIH/genética; VIH-1/genética; Humanos; Inmunoglobulina A/genética; Inmunoglobulina G

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Límite: Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica

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