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ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance.
Mellone, Massimiliano; Piotrowska, Klaudia; Venturi, Giulia; James, Lija; Bzura, Aleksandra; Lopez, Maria A; James, Sonya; Wang, Chuan; Ellis, Matthew J; Hanley, Christopher J; Buckingham, Josephine F; Cox, Kerry L; Hughes, Gareth; Valge-Archer, Viia; King, Emma V; Beers, Stephen A; Jaquet, Vincent; Jones, George D D; Savelyeva, Natalia; Sayan, Emre; Parsons, Jason L; Durant, Stephen; Thomas, Gareth J.
Afiliación
  • Mellone M; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Piotrowska K; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Venturi G; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • James L; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Bzura A; Department of Genetics and Genome Biology, Cancer Research Centre, University of Leicester, Leicester, United Kingdom.
  • Lopez MA; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • James S; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Wang C; Department of Molecular and Clinical Cancer Medicine, Cancer Research Centre, University of Liverpool, Liverpool, United Kingdom.
  • Ellis MJ; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Hanley CJ; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Buckingham JF; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Cox KL; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Hughes G; Bioscience, Oncology Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
  • Valge-Archer V; Bioscience, Oncology Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
  • King EV; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Beers SA; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Jaquet V; Department of Pathology and Immunology, Centre Médical Universitaire, Genève, Switzerland.
  • Jones GDD; Department of Genetics and Genome Biology, Cancer Research Centre, University of Leicester, Leicester, United Kingdom.
  • Savelyeva N; Department of Molecular and Clinical Cancer Medicine, Cancer Research Centre, University of Liverpool, Liverpool, United Kingdom.
  • Sayan E; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Parsons JL; Department of Molecular and Clinical Cancer Medicine, Cancer Research Centre, University of Liverpool, Liverpool, United Kingdom.
  • Durant S; Bioscience, Oncology Innovative Medicines and Early Development (IMED) Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
  • Thomas GJ; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Cancer Res ; 82(24): 4571-4585, 2022 12 16.
Article en En | MEDLINE | ID: mdl-36353752

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de la Ataxia Telangiectasia Mutada / Fibroblastos Asociados al Cáncer / Inmunoterapia / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Res Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de la Ataxia Telangiectasia Mutada / Fibroblastos Asociados al Cáncer / Inmunoterapia / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Res Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido