Brain stem encephalitis is a rare complication of COVID-19.
J Neuroimmunol
; 374: 578007, 2023 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-36481703
ABSTRACT
Here, we describe the clinical phenotype of SARS-CoV-2-related CNS disease and evaluate the SARS-CoV-2 antibody index as a tool to differentiate between a direct (viral) and indirect etiology. Out of >4000 hospitalized patients with COVID-19, we included 13 patients with neurological symptoms with suspicion of neuroinflammation. On clinical grounds, eight were classified as having a possible/probable relationship between neurological symptoms and COVID-19. A clinically distinctive phenotype of brainstem and cerebellar symptoms was seen in 6/8 patients. As we found a positive SARS-CoV-2 antibody index in 3/5 patients, indicating specific intrathecal SARS-CoV-2 IgG production, a direct link with SARS-CoV-2 is likely.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Encefalitis
/
COVID-19
Límite:
Humans
Idioma:
En
Revista:
J Neuroimmunol
Año:
2023
Tipo del documento:
Article