Drug repurposing based novel anti-leishmanial drug screening using <i>in-silico</i> and <i>in-vitro</i> approaches.

Rai, Praveen; Arya, Hemant; Saha, Satabdi; Kumar, Diwakar; Bhatt, Tarun Kumar

Drug repurposing based novel anti-leishmanial drug screening using in-silico and in-vitro approaches.

Rai, Praveen; Arya, Hemant; Saha, Satabdi; Kumar, Diwakar; Bhatt, Tarun Kumar.

Afiliación

Rai P; Department of Biotechnology, Central University of Rajasthan, Ajmer, India.
Arya H; Department of Biotechnology, Central University of Rajasthan, Ajmer, India.
Saha S; Department of Microbiology, Assam University, Silchar, India.
Kumar D; Department of Microbiology, Assam University, Silchar, India.
Bhatt TK; Department of Biotechnology, Central University of Rajasthan, Ajmer, India.

J Biomol Struct Dyn ; 40(21): 10812-10820, 2022.

Article en En | MEDLINE | ID: mdl-36529188

Asunto(s)

Antiprotozoarios; Leishmania donovani; Leishmania; Leishmaniasis Visceral; Humanos; Reposicionamiento de Medicamentos; Antiprotozoarios/farmacología; Antiprotozoarios/química; Evaluación Preclínica de Medicamentos; ADN Primasa/metabolismo; ADN Primasa/farmacología; Leishmaniasis Visceral/tratamiento farmacológico; Leishmaniasis Visceral/parasitología; Simulación de Dinámica Molecular

Palabras clave

Visceral leishmaniasis; drug repurposing; in vitro anti-leishmaniasis drug screening; molecular docking and dynamics simulations; primase

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leishmania donovani / Leishmania / Leishmaniasis Visceral / Antiprotozoarios Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: J Biomol Struct Dyn Año: 2022 Tipo del documento: Article País de afiliación: India

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