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Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modelling.
Barber, Jill; Al-Majdoub, Zubida M; Couto, Narciso; Howard, Martyn; Elmorsi, Yasmine; Scotcher, Daniel; Alizai, Naved; de Wildt, Saskia; Stader, Felix; Sepp, Armin; Rostami-Hodjegan, Amin; Achour, Brahim.
Afiliación
  • Barber J; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom.
  • Al-Majdoub ZM; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom.
  • Couto N; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom.
  • Howard M; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom.
  • Elmorsi Y; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom.
  • Scotcher D; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom.
  • Alizai N; Leeds Teaching Hospitals, Leeds, United Kingdom.
  • de Wildt S; Radboud University Medical Center, Radboud University, Nijmegen, the Netherlands.
  • Stader F; Certara UK Ltd. (Simcyp Division), Sheffield, United Kingdom.
  • Sepp A; Certara UK Ltd. (Simcyp Division), Sheffield, United Kingdom.
  • Rostami-Hodjegan A; Centre for Applied Pharmacokinetic Research, the University of Manchester, Manchester, United Kingdom; Certara UK Ltd. (Simcyp Division), Sheffield, United Kingdom.
  • Achour B; Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, 495A Avedisian Hall, 7 Greenhouse Road, Kingston, RI 02881, United States. Electronic address: achour@uri.edu.
Eur J Pharm Sci ; 182: 106375, 2023 Mar 01.
Article en En | MEDLINE | ID: mdl-36626943
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Productos Biológicos Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Newborn Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Productos Biológicos Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Newborn Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido