Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage.

Lemarié, Fanny L; Sanders, Shaun S; Nguyen, Yen; Martin, Dale D O; Hayden, Michael R

Lemarié, Fanny L; Sanders, Shaun S; Nguyen, Yen; Martin, Dale D O; Hayden, Michael R.

Afiliación

Lemarié FL; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Sanders SS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Nguyen Y; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Martin DDO; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.

Front Physiol ; 14: 1086112, 2023.

Article en En | MEDLINE | ID: mdl-36711022

Palabras clave

HTT; fatty acylation; huntingtin; huntington disease; myristoylation and palmitoylation; post-translational modification (PTM)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Front Physiol Año: 2023 Tipo del documento: Article País de afiliación: Canadá

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