Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin-Deficient Mice via Upregulation of Angiotensin (1-7).

Karasaki, Kohei; Kokubo, Hiroki; Bumdelger, Batmunkh; Kaji, Nobuchika; Sakai, Chiemi; Ishida, Mari; Yoshizumi, Masao

Karasaki, Kohei; Kokubo, Hiroki; Bumdelger, Batmunkh; Kaji, Nobuchika; Sakai, Chiemi; Ishida, Mari; Yoshizumi, Masao.

Afiliación

Karasaki K; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Kokubo H; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Bumdelger B; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Kaji N; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Sakai C; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Ishida M; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Yoshizumi M; Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.

J Am Heart Assoc ; 12(3): e027589, 2023 02 07.

Article en En | MEDLINE | ID: mdl-36718875

Asunto(s)

Bloqueadores del Receptor Tipo 1 de Angiotensina II; Aneurisma de la Aorta Abdominal; Animales; Ratones; Angiotensina II/farmacología; Bloqueadores del Receptor Tipo 1 de Angiotensina II/uso terapéutico; Aorta Abdominal/patología; Aneurisma de la Aorta Abdominal/genética; Aneurisma de la Aorta Abdominal/prevención & control; Modelos Animales de Enfermedad; Proteínas Quinasas JNK Activadas por Mitógenos/metabolismo; Ligandos; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones Endogámicos C57BL; Ratones Noqueados; Osteoprotegerina/genética; Osteoprotegerina/metabolismo; Factores de Necrosis Tumoral/genética; Factores de Necrosis Tumoral/metabolismo; Factores de Necrosis Tumoral/farmacología; Regulación hacia Arriba

Palabras clave

abdominal aortic aneurysm; angiotensin (17); angiotensin II type 1 receptor blocker; osteoprotegerin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Abdominal / Bloqueadores del Receptor Tipo 1 de Angiotensina II Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Am Heart Assoc Año: 2023 Tipo del documento: Article

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