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Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis.
Cooley, Joseph C; Javkhlan, Nomin; Wilson, Jasmine A; Foster, Daniel G; Edelman, Benjamin L; Ortiz, Luis A; Schwartz, David A; Riches, David Wh; Redente, Elizabeth F.
Afiliación
  • Cooley JC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA.
  • Javkhlan N; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Wilson JA; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colorado, USA.
  • Foster DG; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colorado, USA.
  • Edelman BL; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Ortiz LA; Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colorado, USA.
  • Schwartz DA; Department of Environmental and Occupational Health, Graduate School of Public Health at the University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Riches DW; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Redente EF; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
JCI Insight ; 8(3)2023 02 08.
Article en En | MEDLINE | ID: mdl-36752201
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Silicosis / Enfermedades Pulmonares Intersticiales / Fibrosis Pulmonar Idiopática Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: JCI Insight Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Silicosis / Enfermedades Pulmonares Intersticiales / Fibrosis Pulmonar Idiopática Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: JCI Insight Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos