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Structure- and Data-Driven Protein Engineering of Transaminases for Improving Activity and Stereoselectivity.
Ao, Yu-Fei; Pei, Shuxin; Xiang, Chao; Menke, Marian J; Shen, Lin; Sun, Chenghai; Dörr, Mark; Born, Stefan; Höhne, Matthias; Bornscheuer, Uwe T.
Afiliación
  • Ao YF; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.
  • Pei S; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North First Street 2, Beijing, 100190, China.
  • Xiang C; University of Chinese Academy of Sciences, Yuquan Road 19(A), Beijing, 100049, China.
  • Menke MJ; Key Laboratory of Theoretical and Computational Photochemistry of Ministry of Education, College of Chemistry, Beijing Normal University, Xinjiekouwai Street 19, Beijing, 100875, China.
  • Shen L; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.
  • Sun C; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.
  • Dörr M; Key Laboratory of Theoretical and Computational Photochemistry of Ministry of Education, College of Chemistry, Beijing Normal University, Xinjiekouwai Street 19, Beijing, 100875, China.
  • Born S; Yantai-Jingshi Institute of Material Genome Engineering, Nanchang Road 48, Yantai, Shandong, 265505, China.
  • Höhne M; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.
  • Bornscheuer UT; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.
Angew Chem Int Ed Engl ; 62(23): e202301660, 2023 06 05.
Article en En | MEDLINE | ID: mdl-37022103
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Transaminasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Angew Chem Int Ed Engl Año: 2023 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Transaminasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Angew Chem Int Ed Engl Año: 2023 Tipo del documento: Article País de afiliación: Alemania