Copper(I)-Catalyzed Regio- and Stereoselective Silaboration of Terminal Allenes.
ACS Org Inorg Au
; 3(2): 104-108, 2023 Apr 05.
Article
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| MEDLINE
| ID: mdl-37035279
ABSTRACT
Organic compounds bearing both silyl and boryl groups are important building blocks in organic synthesis because of the adequate reactivity of the silyl and boryl groups and high stereospecificity in their derivatization reactions. The difference in reactivity between the silyl and boryl groups enables stepwise derivatization of these groups to afford complex molecules. Here, we report the copper(I)-catalyzed silaboration of terminal allenes to produce multisubstituted allylic boronates embedded with an alkenyl silane structure. The reaction can proceed with a variety of allenes and silylboranes. Furthermore, the silyl and boryl groups were successfully converted into other functional groups, while retaining the stereochemistry of the alkene moiety.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
ACS Org Inorg Au
Año:
2023
Tipo del documento:
Article
País de afiliación:
Japón