Modulation of Cellular Senescence in HEK293 and HepG2 Cells by Ultrafiltrates UPla and ULu Is Partly Mediated by Modulation of Mitochondrial Homeostasis under Oxidative Stress.

Zhou, Junxian; Liu, Kang; Bauer, Chris; Bendner, Gerald; Dietrich, Heike; Slivka, Jakub Peter; Wink, Michael; Wong, Michelle B F; Chan, Mike K S; Skutella, Thomas

Zhou, Junxian; Liu, Kang; Bauer, Chris; Bendner, Gerald; Dietrich, Heike; Slivka, Jakub Peter; Wink, Michael; Wong, Michelle B F; Chan, Mike K S; Skutella, Thomas.

Afiliación

Zhou J; Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.
Liu K; Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing 210009, China.
Bauer C; MicroDiscovery, 10405 Berlin, Germany.
Bendner G; Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.
Dietrich H; Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.
Slivka JP; Reviva s.r.o. Pekarska 6, 158 00 Prague, Czech Republic.
Wink M; Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, 69120 Heidelberg, Germany.
Wong MBF; EW European Wellness International GmbH, 72184 Eutingen im Gäu, Germany.
Chan MKS; EW European Wellness International GmbH, 72184 Eutingen im Gäu, Germany.
Skutella T; Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.

Int J Mol Sci ; 24(7)2023 Apr 04.

Article en En | MEDLINE | ID: mdl-37047720

Asunto(s)

Peróxido de Hidrógeno; Ácido Tióctico; Animales; Humanos; Conejos; Especies Reactivas de Oxígeno/metabolismo; Peróxido de Hidrógeno/farmacología; Peróxido de Hidrógeno/metabolismo; Células Hep G2; Ácido Tióctico/metabolismo; Cromatografía Liquida; Células HEK293; Espectrometría de Masas en Tándem; Estrés Oxidativo; Senescencia Celular; beta-Galactosidasa/metabolismo; Transferrinas/metabolismo

Palabras clave

SA-ß-X-gal; cell proliferation; cellular senescence; intracellular ROS; mitochondrial ROS; mitochondrial fission; senescence marker

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Tióctico / Peróxido de Hidrógeno Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Alemania

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google