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Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding.
Kulakova, Alina; Augustijn, Dillen; El Bialy, Inas; Gentiluomo, Lorenzo; Greco, Maria Laura; Hervø-Hansen, Stefan; Indrakumar, Sowmya; Mahapatra, Sujata; Martinez Morales, Marcello; Pohl, Christin; Polimeni, Marco; Roche, Aisling; Svilenov, Hristo L; Tosstorff, Andreas; Zalar, Matja; Curtis, Robin; Derrick, Jeremy P; Frieß, Wolfgang; Golovanov, Alexander P; Lund, Mikael; Nørgaard, Allan; Khan, Tarik A; Peters, Günther H J; Pluen, Alain; Roessner, Dierk; Streicher, Werner W; van der Walle, Christopher F; Warwicker, Jim; Uddin, Shahid; Winter, Gerhard; Bukrinski, Jens Thostrup; Rinnan, Åsmund; Harris, Pernille.
Afiliación
  • Kulakova A; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, Kongens, Lyngby 2800, Denmark.
  • Augustijn D; Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej 26, Frederiksberg 1958, Denmark.
  • El Bialy I; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universitaet Muenchen, Butenandtstrasse 5, Munich 81377, Germany.
  • Gentiluomo L; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universitaet Muenchen, Butenandtstrasse 5, Munich 81377, Germany.
  • Greco ML; Wyatt Technology Europe GmbH, Hochstrasse 18, Dernbach 56307, Germany.
  • Hervø-Hansen S; Dosage Form Design and Development, AstraZeneca, Sir Aaron Klug Building, Granta Park, Cambridge CB21 6GH, U.K.
  • Indrakumar S; Division of Theoretical Chemistry, Department of Chemistry, Lund University, P.O. Box 124, Lund 22100, Sweden.
  • Mahapatra S; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, Kongens, Lyngby 2800, Denmark.
  • Martinez Morales M; Novozymes A/S, Krogshoejvej 36, Bagsvaerd 2880, Denmark.
  • Pohl C; Dosage Form Design and Development, AstraZeneca, Sir Aaron Klug Building, Granta Park, Cambridge CB21 6GH, U.K.
  • Polimeni M; Novozymes A/S, Krogshoejvej 36, Bagsvaerd 2880, Denmark.
  • Roche A; Division of Theoretical Chemistry, Department of Chemistry, Lund University, P.O. Box 124, Lund 22100, Sweden.
  • Svilenov HL; Department of Chemical Engineering, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
  • Tosstorff A; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universitaet Muenchen, Butenandtstrasse 5, Munich 81377, Germany.
  • Zalar M; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universitaet Muenchen, Butenandtstrasse 5, Munich 81377, Germany.
  • Curtis R; Department of Chemistry, School of Natural Sciences, Faculty of Science and Engineering, and Manchester Institute of Biotechnology, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
  • Derrick JP; Department of Chemical Engineering, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
  • Frieß W; School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, U.K.
  • Golovanov AP; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universitaet Muenchen, Butenandtstrasse 5, Munich 81377, Germany.
  • Lund M; Department of Chemistry, School of Natural Sciences, Faculty of Science and Engineering, and Manchester Institute of Biotechnology, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
  • Nørgaard A; Division of Theoretical Chemistry, Department of Chemistry, Lund University, P.O. Box 124, Lund 22100, Sweden.
  • Khan TA; Novozymes A/S, Krogshoejvej 36, Bagsvaerd 2880, Denmark.
  • Peters GHJ; Pharmaceutical Development & Supplies, Pharma Technical Development Biologics Europe, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, Basel 4070, Switzerland.
  • Pluen A; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, Kongens, Lyngby 2800, Denmark.
  • Roessner D; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, U.K.
  • Streicher WW; Wyatt Technology Europe GmbH, Hochstrasse 18, Dernbach 56307, Germany.
  • van der Walle CF; Novozymes A/S, Krogshoejvej 36, Bagsvaerd 2880, Denmark.
  • Warwicker J; Dosage Form Design and Development, AstraZeneca, Sir Aaron Klug Building, Granta Park, Cambridge CB21 6GH, U.K.
  • Uddin S; School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, U.K.
  • Winter G; Dosage Form Design and Development, AstraZeneca, Sir Aaron Klug Building, Granta Park, Cambridge CB21 6GH, U.K.
  • Bukrinski JT; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universitaet Muenchen, Butenandtstrasse 5, Munich 81377, Germany.
  • Rinnan Å; CMCAssist ApS, Ole Maaløes Vej 3, Copenhagen N 2200, Denmark.
  • Harris P; Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej 26, Frederiksberg 1958, Denmark.
Mol Pharm ; 20(6): 2951-2965, 2023 06 05.
Article en En | MEDLINE | ID: mdl-37146162
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quimiometría / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quimiometría / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca